Untreated Addiction & Other Diseases | Center on Addiction

Effects of Risky Drinking, Tobacco and Drug Use

Effects of Risky Drinking, Tobacco and Drug Use  


Untreated addiction and risky use - content

Tobacco, alcohol and drug use cause or contribute to more than 70 other conditions requiring medical care, including:  

  • Cancer of the bladder, esophagus, larynx, lung, liver, pancreas, breast and mouth 
  • Heart disease and stroke 
  • Pulmonary disease 
  • Cirrhosis
  • Pancreatitis
  • Pregnancy complications
  • Infectious diseases such as HIV and hepatitis
  • Accidents and trauma 

Substance use also co-occurs with and, in some cases, may cause or worsen a range of other medical conditions, including depression, anxiety, post-traumatic stress disorder, bipolar disorder, schizophrenia, attention deficit hyperactivity disorder (ADHD), conduct disorder, eating disorders, various cancers and cardiovascular diseases, and gastrointestinal problems.

Tobacco, alcohol and drug use are responsible for more than 20% of all deaths in the U.S. each year.


  • CASAColumbia. (2012). Addiction medicine: Closing the gap between science and practice.
16% of state budget funds are spent on risky substance use and addiction.

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